The research is an important step to one day helping people who have experienced the loss of a limb and opens the door to the potential use of a similar treatment on humans in the future.
Like humans, the African Clawed Frog used in the research does not have the ability to naturally regenerate a limb like some other critters. It was treated with a five-drug cocktail over 24 hours. That brief treatment set in motion an 18-month period of regrowth that restored a functional leg.
“It’s exciting to see that the drugs we selected were helping to create an almost complete limb,” said Nirosha Murugan, research affiliate at the Allen Discovery Center at Tufts and first author of the paper outlining the experiment.